An efficient method to identify virus-specific TCRs for TCR-T cell immunotherapy against virus-associated malignancies

Adoptive transfer of T cells genetically engineered with a T cell receptor (TCR) is a promising cancer treatment modality that requires the identification of TCRs with good characteristics. Most T cell cloning methods involve a stringent singularization process, which necessitates either tedious han...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Dong, Lianhua, Ma, Yipeng, Wang, Juntao, Qiao, Dongjuan, Tian, Geng, Wang, Mingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480097/
https://www.ncbi.nlm.nih.gov/pubmed/34583647
http://dx.doi.org/10.1186/s12865-021-00455-3

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