The microglial NLRP3 inflammasome is involved in human SARS-CoV-2 cerebral pathogenicity: A report of three post-mortem cases

We herein report, by using confocal immunofluorescence, the colocalization of the SARS-CoV-2 nucleocapsid within neurons, astrocytes, oligodendrocytes and microglia in three deceased COVID-19 cases, of between 78 and 85 years of age at death. The viral nucleocapsid was detected together with its ACE...

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Detalles Bibliográficos
Autores principales: Cama, Viviana Falcón, Marín-Prida, Javier, Acosta-Rivero, Nelson, Acosta, Emilio F., Díaz, Leonardo Oramas, Casadesús, Ana V., Fernández-Marrero, Briandy, Gilva-Rodríguez, Nathalie, Cremata-García, Daina, Cervantes-Llanos, Majel, Piniella-Matamoros, Beatriz, Sánchez, Daisy, del Rosario-Cruz, Leticia, Borrajero, Israel, Díaz, Angelina, González, Yorexis, Pentón-Arias, Eduardo, Montero-González, Teresita, Guillen-Nieto, Gerardo, Pentón-Rol, Giselle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480138/
https://www.ncbi.nlm.nih.gov/pubmed/34619427
http://dx.doi.org/10.1016/j.jneuroim.2021.577728

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