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Discovery of Genes that Modulate Flavivirus Replication in an Interferon-Dependent Manner

Establishment of the interferon (IFN)-mediated antiviral state provides a crucial initial line of defense against viral infection. Numerous genes that contribute to this antiviral state remain to be identified. Using a loss-of-function strategy, we screened an original library of 1156 siRNAs targeti...

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Detalles Bibliográficos
Autores principales: Lesage, Sarah, Chazal, Maxime, Beauclair, Guillaume, Batalie, Damien, Cerboni, Silvia, Couderc, Elodie, Lescure, Aurianne, Del Nery, Elaine, Tangy, Frédéric, Martin, Annette, Manel, Nicolas, Jouvenet, Nolwenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480147/
https://www.ncbi.nlm.nih.gov/pubmed/34599939
http://dx.doi.org/10.1016/j.jmb.2021.167277