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The Tumorigenic Effect of Sphingosine Kinase 1 and Its Potential Therapeutic Target

Sphingosine kinase 1 (SPHK1) regulates cell proliferation and survival by converting sphingosine to the signaling mediator sphingosine 1-phosphate (S1P). SPHK1 is widely overexpressed in most cancers, promoting tumor progression and is associated with clinical prognosis. Numerous studies have explor...

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Detalles Bibliográficos
Autores principales:	Wang, Xianwang, Sun, Yong, Peng, Xiaochun, Naqvi, Syed Manzar Abbas Shah, Yang, Yue, Zhang, Jing, Chen, Meiwen, Chen, Yuan, Chen, Hongyue, Yan, Huizi, Wei, Guangliang, Hong, Peng, Lu, Yingying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480355/ https://www.ncbi.nlm.nih.gov/pubmed/33317322 http://dx.doi.org/10.1177/1073274820976664

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