TIMP1 expression underlies sex disparity in liver metastasis and survival in pancreatic cancer

Sex disparity in cancer is so far inadequately considered, and components of its basis are rather unknown. We reveal that male versus female pancreatic cancer (PC) patients and mice show shortened survival, more frequent liver metastasis, and elevated hepatic metastasis-promoting gene expression. Ti...

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Detalles Bibliográficos
Autores principales: Hermann, Chris D., Schoeps, Benjamin, Eckfeld, Celina, Munkhbaatar, Enkhtsetseg, Kniep, Lukas, Prokopchuk, Olga, Wirges, Nils, Steiger, Katja, Häußler, Daniel, Knolle, Percy, Poulton, Emily, Khokha, Rama, Grünwald, Barbara T., Demir, Ihsan Ekin, Krüger, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480668/
https://www.ncbi.nlm.nih.gov/pubmed/34533565
http://dx.doi.org/10.1084/jem.20210911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480668/
https://www.ncbi.nlm.nih.gov/pubmed/34533565
http://dx.doi.org/10.1084/jem.20210911

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