Intercrypt sentinel macrophages tune antibacterial NF-κB responses in gut epithelial cells via TNF

Intestinal epithelial cell (IEC) NF-κB signaling regulates the balance between mucosal homeostasis and inflammation. It is not fully understood which signals tune this balance and how bacterial exposure elicits the process. Pure LPS induces epithelial NF-κB activation in vivo. However, we found that...

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Detalles Bibliográficos
Autores principales: Hausmann, Annika, Felmy, Boas, Kunz, Leo, Kroon, Sanne, Berthold, Dorothée Lisa, Ganz, Giverny, Sandu, Ioana, Nakamura, Toshihiro, Zangger, Nathan Sébastien, Zhang, Yang, Dolowschiak, Tamas, Fattinger, Stefan Alexander, Furter, Markus, Müller-Hauser, Anna Angelika, Barthel, Manja, Vlantis, Katerina, Wachsmuth, Laurens, Kisielow, Jan, Tortola, Luigi, Heide, Danijela, Heikenwälder, Mathias, Oxenius, Annette, Kopf, Manfred, Schroeder, Timm, Pasparakis, Manolis, Sellin, Mikael Erik, Hardt, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480669/
https://www.ncbi.nlm.nih.gov/pubmed/34529751
http://dx.doi.org/10.1084/jem.20210862

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