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Gut epithelial IL-27 confers intestinal immunity through the induction of intraepithelial lymphocytes

IL-27 controls a diverse range of immune responses in many disease settings. Here, we identify intestinal epithelial cells (IECs) as one of the major IL-27 cellular sources in the gut-associated tissue. Unlike IL-27 secreted by innate immune cells, gut epithelial IL-27 is dispensable for T-bet(+) re...

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Detalles Bibliográficos
Autores principales:	Lin, Chia-Hao, Chen, Mei-Chi, Lin, Ling-Li, Christian, David A., Min, Booki, Hunter, Christopher A., Lu, Li-Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480671/ https://www.ncbi.nlm.nih.gov/pubmed/34554189 http://dx.doi.org/10.1084/jem.20210021

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