Molecular dynamics and protein frustration analysis of human fused in Sarcoma protein variants in Amyotrophic Lateral Sclerosis type 6: An In Silico approach

Amyotrophic lateral sclerosis (ALS) is the most frequent adult-onset motor neuron disorder. The disease is characterized by degeneration of upper and lower motor neurons, leading to death usually within five years after the onset of symptoms. While most cases are sporadic, 5%-10% of cases can be ass...

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Detalles Bibliográficos
Autores principales: Bonet, L. F. S., Loureiro, J. P., Pereira, G. R. C., Da Silva, A. N. R., De Mesquita, J. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480726/
https://www.ncbi.nlm.nih.gov/pubmed/34587215
http://dx.doi.org/10.1371/journal.pone.0258061

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