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Anti-inflammatory activity of lefamulin versus azithromycin and dexamethasone in vivo and in vitro in a lipopolysaccharide-induced lung neutrophilia mouse model

Several antibiotics demonstrate both antibacterial and anti-inflammatory/immunomodulatory activities and are used to treat inflammatory pulmonary disorders. Lefamulin is a pleuromutilin antibiotic approved to treat community-acquired bacterial pneumonia (CABP). This study evaluated lefamulin anti-in...

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Detalles Bibliográficos
Autores principales:	Hafner, Michael, Paukner, Susanne, Wicha, Wolfgang W., Hrvačić, Boška, Cedilak, Matea, Faraho, Ivan, Gelone, Steven P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8480901/ https://www.ncbi.nlm.nih.gov/pubmed/34587166 http://dx.doi.org/10.1371/journal.pone.0237659

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