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Polyphyllin I Inhibits Propionibacterium acnes-Induced IL-8 Secretion in HaCaT Cells by Downregulating the CD36/NOX1/ROS/NLRP3/IL-1β Pathway

Acne vulgaris (AV) is a chronic skin disease involving inflammation of the pilosebaceous units. Propionibacterium acnes (P. acnes) hypercolonization is one pathogenic factor for AV. P. acnes that triggers interleukin-1β (IL-1β) by activating the pyrin domain-containing 3 protein (NLRP3) inflammasome...

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Detalles Bibliográficos
Autores principales:	Yang, Shuyun, Jiang, Ying, Yu, Xiuqin, Zhu, Liping, Wang, Lu, Mao, Jingzhu, Wang, Miaomiao, Zhou, Naihui, Yang, Ziliang, Liu, Ying, Zhu, Tingting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481039/ https://www.ncbi.nlm.nih.gov/pubmed/34603464 http://dx.doi.org/10.1155/2021/1821220

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