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The REDD1/TXNIP Complex Accelerates Oxidative Stress-Induced Apoptosis of Nucleus Pulposus Cells through the Mitochondrial Pathway

The death of nucleus pulposus (NP) cells is an important cause of intervertebral disc (IVD) degeneration. Redox disturbance caused by dysfunctional mitochondria has been considered as a vital risk for NP cell survival. It is valuable to identify key proteins maintaining mitochondrial function in NP...

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Detalles Bibliográficos
Autores principales: Yin, Huipeng, Wang, Kun, Das, Abhirup, Li, Gaocai, Song, Yu, Luo, Rongjin, Cheung, Jason Pui Yin, Zhang, Teng, Li, Shuai, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481043/
https://www.ncbi.nlm.nih.gov/pubmed/34603601
http://dx.doi.org/10.1155/2021/7397516