Understanding the Genetic and Molecular Basis of Familial Hypertrophic Cardiomyopathy and the Current Trends in Gene Therapy for Its Management

Hypertrophic cardiomyopathy (HCM) is a genetically acquired disease of cardiac myocytes. Studies show that 70% of this disease is a result of different mutations in various sarcomere genes. This review aims to discuss several genetic mutations, epigenetic factors, and signal transduction pathways le...

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Detalles Bibliográficos
Autores principales: Pradeep, Roshini, Akram, Aqsa, Proute, Matthew C, Kothur, Nageshwar R, Georgiou, Petros, Serhiyenia, Tatsiana, Shi, Wangpan, Kerolos, Mina E, Mostafa, Jihan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481153/
https://www.ncbi.nlm.nih.gov/pubmed/34646605
http://dx.doi.org/10.7759/cureus.17548

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