Multiplex suppression of four quadruplet codons via tRNA directed evolution

Genetic code expansion technologies supplement the natural codon repertoire with assignable variants in vivo, but are often limited by heterologous translational components and low suppression efficiencies. Here, we explore engineered Escherichia coli tRNAs supporting quadruplet codon translation by...

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Detalles Bibliográficos
Autores principales: DeBenedictis, Erika A., Carver, Gavriela D., Chung, Christina Z., Söll, Dieter, Badran, Ahmed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481270/
https://www.ncbi.nlm.nih.gov/pubmed/34588441
http://dx.doi.org/10.1038/s41467-021-25948-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481270/
https://www.ncbi.nlm.nih.gov/pubmed/34588441
http://dx.doi.org/10.1038/s41467-021-25948-y

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