Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury

The purpose of this study was to investigate whether inhibition of DNA (cytosine-5)-methyltransferase 1 (DNMT-1) alleviated ferroptosis through nuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy during diabetes myocardial (DM) ischemia/reperfusion (I/R) injury (IRI). Rat DM + sham (DS),...

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Detalles Bibliográficos
Autores principales: Li, Wenyuan, Li, Wei, Wang, Yao, Leng, Yan, Xia, Zhongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481302/
https://www.ncbi.nlm.nih.gov/pubmed/34588431
http://dx.doi.org/10.1038/s41420-021-00656-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481302/
https://www.ncbi.nlm.nih.gov/pubmed/34588431
http://dx.doi.org/10.1038/s41420-021-00656-0

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