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In vivo quantitative assessment of therapeutic response to bortezomib therapy in disseminated animal models of multiple myeloma with [(18)F]FDG and [(64)Cu]Cu-LLP2A PET

BACKGROUND: Multiple myeloma (MM) is a disease of cancerous plasma cells in the bone marrow. Imaging-based timely determination of therapeutic response is critical for improving outcomes in MM patients. Very late antigen-4 (VLA4, CD49d/CD29) is overexpressed in MM cells. Here, we evaluated [(18)F]FD...

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Detalles Bibliográficos
Autores principales: Ghai, Anchal, Fettig, Nikki, Fontana, Francesca, DiPersio, John, Rettig, Mike, Neal, Julie O., Achilefu, Samuel, Shoghi, Kooresh I., Shokeen, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481408/
https://www.ncbi.nlm.nih.gov/pubmed/34586539
http://dx.doi.org/10.1186/s13550-021-00840-4