USP12 promotes CD4(+) T cell responses through deubiquitinating and stabilizing BCL10

Deubiquitinases (DUBs) regulate diverse biological processes and represent a novel class of drug targets. However, the biological function of only a small fraction of DUBs, especially in adaptive immune response regulation, is well-defined. In this study, we identified DUB ubiquitin-specific peptida...

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Detalles Bibliográficos
Autores principales: Fu, Yuling, Wang, Peng, Zhao, Jingjing, Tan, Yunke, Sheng, Junli, He, Shitong, Du, Xialin, Huang, Yulan, Yang, Yalong, Li, Jinling, Cai, Yuxiong, Liu, Yuxuan, Hu, Shengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481463/
https://www.ncbi.nlm.nih.gov/pubmed/33941870
http://dx.doi.org/10.1038/s41418-021-00787-y

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