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Carbamoyl phosphate and its substitutes for the uracil synthesis in origins of life scenarios

The first step of pyrimidine synthesis along the orotate pathway is studied to test the hypothesis of geochemical continuity of protometabolic pathways at the origins of life. Carbamoyl phosphate (CP) is the first high-energy building block that intervenes in the in vivo synthesis of the uracil ring...

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Detalles Bibliográficos
Autores principales: Ter-Ovanessian, Louis M. P., Rigaud, Baptiste, Mezzetti, Alberto, Lambert, Jean-François, Maurel, Marie-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481487/
https://www.ncbi.nlm.nih.gov/pubmed/34588537
http://dx.doi.org/10.1038/s41598-021-98747-6

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