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Carbamoyl phosphate and its substitutes for the uracil synthesis in origins of life scenarios
The first step of pyrimidine synthesis along the orotate pathway is studied to test the hypothesis of geochemical continuity of protometabolic pathways at the origins of life. Carbamoyl phosphate (CP) is the first high-energy building block that intervenes in the in vivo synthesis of the uracil ring...
Autores principales: | Ter-Ovanessian, Louis M. P., Rigaud, Baptiste, Mezzetti, Alberto, Lambert, Jean-François, Maurel, Marie-Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481487/ https://www.ncbi.nlm.nih.gov/pubmed/34588537 http://dx.doi.org/10.1038/s41598-021-98747-6 |
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