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The Immunoregulatory Role of the Signal Regulatory Protein Family and CD47 Signaling Pathway in Type 1 Diabetes
BACKGROUND: The pathogenesis of type 1 diabetes (T1D) involves complex genetic susceptibility that impacts pathways regulating host immunity and the target of autoimmune attack, insulin-producing pancreatic β-cells. Interactions between risk variants and environmental factors result in significant h...
Autores principales: | Sharp, Robert C., Brown, Matthew E., Shapiro, Melanie R., Posgai, Amanda L., Brusko, Todd M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481641/ https://www.ncbi.nlm.nih.gov/pubmed/34603322 http://dx.doi.org/10.3389/fimmu.2021.739048 |
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