Mitragynine (Kratom)-Induced Cognitive Impairments in Mice Resemble Δ9-THC and Morphine Effects: Reversal by Cannabinoid CB(1) Receptor Antagonism

Kratom is a widely abused plant-based drug preparation with a global interest in recent years, well beyond its native grounds in Southeast Asia. Mitragynine, its major psychoactive constituent is known to exhibit opioid-like behavioral effects with resultant neuroplasticity in the brain reward syste...

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Detalles Bibliográficos
Autores principales: Iman, Ismail Nurul, Ahmad, Nur Aimi Zawami, Mohd Yusof, Nurul Aiman, Talib, Ummi Nasrah, Norazit, Anwar, Kumar, Jaya, Mehat, Muhammad Zulfadli, Hassan, Zurina, Müller, Christian P., Muzaimi, Mustapha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481666/
https://www.ncbi.nlm.nih.gov/pubmed/34603022
http://dx.doi.org/10.3389/fphar.2021.708055

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