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Body Mass Index Changes in Relation to Male Reproductive Hormones: Longitudinal Results From a Community-Based Cohort Study
The objective of the current study was to explore the relationship between longitudinal change in body mass index (BMI) and reproductive hormones in middle-aged and elderly Chinese men. A cohort study was conducted in a rural area of China. Local male residents aged 40–80 years were recruited at bas...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481735/ https://www.ncbi.nlm.nih.gov/pubmed/34581214 http://dx.doi.org/10.1177/15579883211049044 |
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author | Ye, Yun Liang, Qun-Feng Li, Jian-Hui Zheng, Jun-Biao Yu, Xiao-Hua Zhang, Shu-Cheng Zhou, Wei-Jin Shi, Hui-Juan Liang, Guo-Qing Zhu, Qian-Xi |
author_facet | Ye, Yun Liang, Qun-Feng Li, Jian-Hui Zheng, Jun-Biao Yu, Xiao-Hua Zhang, Shu-Cheng Zhou, Wei-Jin Shi, Hui-Juan Liang, Guo-Qing Zhu, Qian-Xi |
author_sort | Ye, Yun |
collection | PubMed |
description | The objective of the current study was to explore the relationship between longitudinal change in body mass index (BMI) and reproductive hormones in middle-aged and elderly Chinese men. A cohort study was conducted in a rural area of China. Local male residents aged 40–80 years were recruited at baseline in 2012 and were followed up in 2016. Information about weight, height, waist circumference, sex hormones, smoking status, and medical history were obtained. The change in BMI reported no significant relationship with the change in total testosterone (TT), calculated free testosterone (cFT), and bioavailable testosterone (BioT) in Pearson correlation analyses. When the change in BMI was divided into three groups—“great loss,” “normal fluctuation,” and “great gain”—TT, cFT and BioT had the highest increase (or the lowest decrease) in men with “normal fluctuation” in BMI compared with the other two groups. The advantage of maintaining a stable BMI was more evident for those who were overweight, non-smoking, and disease-free. There was a tendency of a continuous increase in cFT and BioT with BMI increase in smoking and diseased populations. Maintaining a stable BMI is associated with maintaining normal levels of reproductive hormones, especially in overweight, non-smoking, and healthy men aged over 40 years. |
format | Online Article Text |
id | pubmed-8481735 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-84817352021-10-01 Body Mass Index Changes in Relation to Male Reproductive Hormones: Longitudinal Results From a Community-Based Cohort Study Ye, Yun Liang, Qun-Feng Li, Jian-Hui Zheng, Jun-Biao Yu, Xiao-Hua Zhang, Shu-Cheng Zhou, Wei-Jin Shi, Hui-Juan Liang, Guo-Qing Zhu, Qian-Xi Am J Mens Health Original Article The objective of the current study was to explore the relationship between longitudinal change in body mass index (BMI) and reproductive hormones in middle-aged and elderly Chinese men. A cohort study was conducted in a rural area of China. Local male residents aged 40–80 years were recruited at baseline in 2012 and were followed up in 2016. Information about weight, height, waist circumference, sex hormones, smoking status, and medical history were obtained. The change in BMI reported no significant relationship with the change in total testosterone (TT), calculated free testosterone (cFT), and bioavailable testosterone (BioT) in Pearson correlation analyses. When the change in BMI was divided into three groups—“great loss,” “normal fluctuation,” and “great gain”—TT, cFT and BioT had the highest increase (or the lowest decrease) in men with “normal fluctuation” in BMI compared with the other two groups. The advantage of maintaining a stable BMI was more evident for those who were overweight, non-smoking, and disease-free. There was a tendency of a continuous increase in cFT and BioT with BMI increase in smoking and diseased populations. Maintaining a stable BMI is associated with maintaining normal levels of reproductive hormones, especially in overweight, non-smoking, and healthy men aged over 40 years. SAGE Publications 2021-09-28 /pmc/articles/PMC8481735/ /pubmed/34581214 http://dx.doi.org/10.1177/15579883211049044 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Article Ye, Yun Liang, Qun-Feng Li, Jian-Hui Zheng, Jun-Biao Yu, Xiao-Hua Zhang, Shu-Cheng Zhou, Wei-Jin Shi, Hui-Juan Liang, Guo-Qing Zhu, Qian-Xi Body Mass Index Changes in Relation to Male Reproductive Hormones: Longitudinal Results From a Community-Based Cohort Study |
title | Body Mass Index Changes in Relation to Male Reproductive Hormones: Longitudinal Results From a Community-Based Cohort Study |
title_full | Body Mass Index Changes in Relation to Male Reproductive Hormones: Longitudinal Results From a Community-Based Cohort Study |
title_fullStr | Body Mass Index Changes in Relation to Male Reproductive Hormones: Longitudinal Results From a Community-Based Cohort Study |
title_full_unstemmed | Body Mass Index Changes in Relation to Male Reproductive Hormones: Longitudinal Results From a Community-Based Cohort Study |
title_short | Body Mass Index Changes in Relation to Male Reproductive Hormones: Longitudinal Results From a Community-Based Cohort Study |
title_sort | body mass index changes in relation to male reproductive hormones: longitudinal results from a community-based cohort study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481735/ https://www.ncbi.nlm.nih.gov/pubmed/34581214 http://dx.doi.org/10.1177/15579883211049044 |
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