5,6,7,4'-Tetramethoxyflavanone attenuates NADPH oxidase 1/4 and promotes sirtuin-1 to inhibit cell stress, senescence and apoptosis in Aß25-35–mediated SK-N-SH dysfunction

Amyloidogenesis is a fundamental step of amyloid beta (Aβ) generation-induced toxicity that is commonly reported to disrupt neuronal circuits, function and survival in Alzheimer's disease (AD). The neuroprotective effect of 5,6,7,4'-tetramethoxyflavanone (TMF) from Chormolaela odorata extr...

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Detalles Bibliográficos
Autores principales: Jumnongprakhon, Pichaya, Chokchaisiri, Ratchanaporn, Thummayot, Sarinthorn, Suksamrarn, Apichart, Tocharus, Chainarong, Tocharus, Jiraporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481796/
https://www.ncbi.nlm.nih.gov/pubmed/34602929
http://dx.doi.org/10.17179/excli2021-3841

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