Highlighting the Relevance of CD8(+) T Cells in Filarial Infections

The T cell immune responses in filarial infections are primarily mediated by CD4(+) T cells and type 2-associated cytokines. Emerging evidence indicates that CD8(+) T cell responses are important for anti-filarial immunity, however, could be suppressed in co-infections. This review summarizes what w...

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Autores principales: Kwarteng, Alexander, Asiedu, Ebenezer, Koranteng, Kelvin Kwaku, Asiedu, Samuel Opoku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481813/
https://www.ncbi.nlm.nih.gov/pubmed/34603287
http://dx.doi.org/10.3389/fimmu.2021.714052
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author Kwarteng, Alexander
Asiedu, Ebenezer
Koranteng, Kelvin Kwaku
Asiedu, Samuel Opoku
author_facet Kwarteng, Alexander
Asiedu, Ebenezer
Koranteng, Kelvin Kwaku
Asiedu, Samuel Opoku
author_sort Kwarteng, Alexander
collection PubMed
description The T cell immune responses in filarial infections are primarily mediated by CD4(+) T cells and type 2-associated cytokines. Emerging evidence indicates that CD8(+) T cell responses are important for anti-filarial immunity, however, could be suppressed in co-infections. This review summarizes what we know so far about the activities of CD8(+) T cell responses in filarial infections, co-infections, and the associations with the development of filarial pathologies.
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spelling pubmed-84818132021-10-01 Highlighting the Relevance of CD8(+) T Cells in Filarial Infections Kwarteng, Alexander Asiedu, Ebenezer Koranteng, Kelvin Kwaku Asiedu, Samuel Opoku Front Immunol Immunology The T cell immune responses in filarial infections are primarily mediated by CD4(+) T cells and type 2-associated cytokines. Emerging evidence indicates that CD8(+) T cell responses are important for anti-filarial immunity, however, could be suppressed in co-infections. This review summarizes what we know so far about the activities of CD8(+) T cell responses in filarial infections, co-infections, and the associations with the development of filarial pathologies. Frontiers Media S.A. 2021-09-16 /pmc/articles/PMC8481813/ /pubmed/34603287 http://dx.doi.org/10.3389/fimmu.2021.714052 Text en Copyright © 2021 Kwarteng, Asiedu, Koranteng and Asiedu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Kwarteng, Alexander
Asiedu, Ebenezer
Koranteng, Kelvin Kwaku
Asiedu, Samuel Opoku
Highlighting the Relevance of CD8(+) T Cells in Filarial Infections
title Highlighting the Relevance of CD8(+) T Cells in Filarial Infections
title_full Highlighting the Relevance of CD8(+) T Cells in Filarial Infections
title_fullStr Highlighting the Relevance of CD8(+) T Cells in Filarial Infections
title_full_unstemmed Highlighting the Relevance of CD8(+) T Cells in Filarial Infections
title_short Highlighting the Relevance of CD8(+) T Cells in Filarial Infections
title_sort highlighting the relevance of cd8(+) t cells in filarial infections
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481813/
https://www.ncbi.nlm.nih.gov/pubmed/34603287
http://dx.doi.org/10.3389/fimmu.2021.714052
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