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COVID-19 Vaccination in Pregnancy and Lactation: Current Research and Gaps in Understanding

The COVID-19 pandemic has demonstrated the urgent need to develop vaccine strategies optimized for pregnant people and their newborns, as both populations are at risk of developing severe disease. Although not included in COVID-19 vaccine development trials, pregnant people have had access to these...

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Autores principales: Shook, Lydia L., Fallah, Parisa N., Silberman, Jason N., Edlow, Andrea G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481914/
https://www.ncbi.nlm.nih.gov/pubmed/34604115
http://dx.doi.org/10.3389/fcimb.2021.735394
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author Shook, Lydia L.
Fallah, Parisa N.
Silberman, Jason N.
Edlow, Andrea G.
author_facet Shook, Lydia L.
Fallah, Parisa N.
Silberman, Jason N.
Edlow, Andrea G.
author_sort Shook, Lydia L.
collection PubMed
description The COVID-19 pandemic has demonstrated the urgent need to develop vaccine strategies optimized for pregnant people and their newborns, as both populations are at risk of developing severe disease. Although not included in COVID-19 vaccine development trials, pregnant people have had access to these vaccines since their initial release in the US and abroad. The rapid development and distribution of novel COVID-19 vaccines to people at risk, including those who are pregnant and lactating, presents an unprecedented opportunity to further our understanding of vaccine-induced immunity in these populations. In this review, we aim to summarize the literature to date on COVID-19 vaccination in pregnancy and lactation and highlight opportunities for investigation that may inform future maternal vaccine development and implementation strategies.
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spelling pubmed-84819142021-10-01 COVID-19 Vaccination in Pregnancy and Lactation: Current Research and Gaps in Understanding Shook, Lydia L. Fallah, Parisa N. Silberman, Jason N. Edlow, Andrea G. Front Cell Infect Microbiol Cellular and Infection Microbiology The COVID-19 pandemic has demonstrated the urgent need to develop vaccine strategies optimized for pregnant people and their newborns, as both populations are at risk of developing severe disease. Although not included in COVID-19 vaccine development trials, pregnant people have had access to these vaccines since their initial release in the US and abroad. The rapid development and distribution of novel COVID-19 vaccines to people at risk, including those who are pregnant and lactating, presents an unprecedented opportunity to further our understanding of vaccine-induced immunity in these populations. In this review, we aim to summarize the literature to date on COVID-19 vaccination in pregnancy and lactation and highlight opportunities for investigation that may inform future maternal vaccine development and implementation strategies. Frontiers Media S.A. 2021-09-16 /pmc/articles/PMC8481914/ /pubmed/34604115 http://dx.doi.org/10.3389/fcimb.2021.735394 Text en Copyright © 2021 Shook, Fallah, Silberman and Edlow https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Shook, Lydia L.
Fallah, Parisa N.
Silberman, Jason N.
Edlow, Andrea G.
COVID-19 Vaccination in Pregnancy and Lactation: Current Research and Gaps in Understanding
title COVID-19 Vaccination in Pregnancy and Lactation: Current Research and Gaps in Understanding
title_full COVID-19 Vaccination in Pregnancy and Lactation: Current Research and Gaps in Understanding
title_fullStr COVID-19 Vaccination in Pregnancy and Lactation: Current Research and Gaps in Understanding
title_full_unstemmed COVID-19 Vaccination in Pregnancy and Lactation: Current Research and Gaps in Understanding
title_short COVID-19 Vaccination in Pregnancy and Lactation: Current Research and Gaps in Understanding
title_sort covid-19 vaccination in pregnancy and lactation: current research and gaps in understanding
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481914/
https://www.ncbi.nlm.nih.gov/pubmed/34604115
http://dx.doi.org/10.3389/fcimb.2021.735394
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