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The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure

BACKGROUND: Studies reporting accelerated ageing in children with affective disorders or maltreatment exposure have relied on algorithms for estimating epigenetic age derived from adult samples. These algorithms have limited validity for epigenetic age estimation during early development. We here us...

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Detalles Bibliográficos
Autores principales: Dammering, Felix, Martins, Jade, Dittrich, Katja, Czamara, Darina, Rex-Haffner, Monika, Overfeld, Judith, de Punder, Karin, Buss, Claudia, Entringer, Sonja, Winter, Sibylle M., Binder, Elisabeth B., Heim, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482287/
https://www.ncbi.nlm.nih.gov/pubmed/34621920
http://dx.doi.org/10.1016/j.ynstr.2021.100394