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Discovering a qualitative transcriptional signature of homologous recombination defectiveness for prostate cancer

The discovery of homologous recombination deficiency (HRD) biomarkers in prostate cancer is important for patients who will benefit from poly ADP-ribose polymerase inhibitor (PARPi). Here, we developed a transcriptional homologous recombination defectiveness (HRDness) signature, comprising 16 gene p...

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Detalles Bibliográficos
Autores principales:	Li, Yawei, Zhao, Zhangxiang, Ai, Liqiang, Wang, Yuquan, Liu, Kaidong, Chen, Bo, Chen, Tingting, Zhuang, Shuping, Xu, Huanhuan, Zou, Min, Gu, Yunyan, Li, Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482486/ https://www.ncbi.nlm.nih.gov/pubmed/34622176 http://dx.doi.org/10.1016/j.isci.2021.103135

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