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Identification and validation of pivotal genes related to age-related meniscus degeneration based on gene expression profiling analysis and in vivo and in vitro models detection
BACKGROUND: The componential and structural change in the meniscus with aging would increase the tissue vulnerability of the meniscus, which would induce meniscus tearing. Here, we investigated the molecular mechanism of age-related meniscus degeneration with gene expression profiling analysis, and...
Autores principales: | Chen, Ming, Zhou, Siqi, Shi, Huasong, Gu, Hanwen, Wen, Yinxian, Chen, Liaobin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482591/ https://www.ncbi.nlm.nih.gov/pubmed/34587952 http://dx.doi.org/10.1186/s12920-021-01088-6 |
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