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Genetic interference exerted by Salmonella-delivered CRISPR/Cas9 significantly reduces the pathological burden caused by Marek’s disease virus in chickens

Efficient in vivo delivery of a CRISPR/Cas9 plasmid is of paramount importance for effective therapy. Here, we investigated the usability of Salmonella as a plasmid carrier for in vivo therapy against virus-induced cancer using Marek’s disease virus (MDV) as a model for study in chickens. A green fl...

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Detalles Bibliográficos
Autores principales:	Senevirathne, Amal, Hewawaduge, Chamith, Lee, John Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482593/ https://www.ncbi.nlm.nih.gov/pubmed/34593043 http://dx.doi.org/10.1186/s13567-021-00995-x

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