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PAM-repeat associations and spacer selection preferences in single and co-occurring CRISPR-Cas systems

BACKGROUND: The adaptive CRISPR-Cas immune system stores sequences from past invaders as spacers in CRISPR arrays and thereby provides direct evidence that links invaders to hosts. Mapping CRISPR spacers has revealed many aspects of CRISPR-Cas biology, including target requirements such as the proto...

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Detalles Bibliográficos
Autores principales:	Vink, Jochem N. A., Baijens, Jan H. L., Brouns, Stan J. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482600/ https://www.ncbi.nlm.nih.gov/pubmed/34593010 http://dx.doi.org/10.1186/s13059-021-02495-9

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