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Divergent patterns of selection on metabolite levels and gene expression

BACKGROUND: Natural selection can act on multiple genes in the same pathway, leading to polygenic adaptation. For example, adaptive changes were found to down-regulate six genes involved in ergosterol biosynthesis—an essential pathway targeted by many antifungal drugs—in some strains of the yeast Sa...

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Detalles Bibliográficos
Autores principales:	Kern, Alexander F., Yang, Grace Xiaolu, Khosla, Neil M., Ang, Roy Moh Lik, Snyder, Michael P., Fraser, Hunter B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482673/ https://www.ncbi.nlm.nih.gov/pubmed/34587900 http://dx.doi.org/10.1186/s12862-021-01915-5

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