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Integrative analysis of genome-wide DNA methylation and single-nucleotide polymorphism identified ACSM5 as a suppressor of lumbar ligamentum flavum hypertrophy

BACKGROUND: Hypertrophy of ligamentum flavum (HLF) is a common lumbar degeneration disease (LDD) with typical symptoms of low back pain and limb numbness owing to an abnormal pressure on spinal nerves. Previous studies revealed HLF might be caused by fibrosis, inflammatory, and other bio-pathways. H...

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Detalles Bibliográficos
Autores principales:	Cao, Yanlin, Zhan, Yenan, Qiu, Sujun, Chen, Zhong, Gong, Kaiqin, Ni, Songjia, Duan, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482693/ https://www.ncbi.nlm.nih.gov/pubmed/34593020 http://dx.doi.org/10.1186/s13075-021-02625-5

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