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Development of a Prodrug of Camptothecin for Enhanced Treatment of Glioblastoma Multiforme

[Image: see text] A novel therapeutic approach for glioblastoma multiforme (GBM) therapy has been carried out through in vitro and in vivo testing by using the prodrug camptothecin-20-O-(5-aminolevulinate) (CPT-ALA). The incorporation of ALA to CPT may promote uptake of the cytotoxic molecule by gli...

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Detalles Bibliográficos
Autores principales:	Checa-Chavarria, Elisa, Rivero-Buceta, Eva, Sanchez Martos, Miguel Angel, Martinez Navarrete, Gema, Soto-Sánchez, Cristina, Botella, Pablo, Fernández, Eduardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482753/ https://www.ncbi.nlm.nih.gov/pubmed/33645231 http://dx.doi.org/10.1021/acs.molpharmaceut.0c00968

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