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Identification, selection, and expansion of non-gene modified alloantigen-reactive Tregs for clinical therapeutic use

Transplantation is limited by the need for life-long pharmacological immunosuppression, which carries significant morbidity and mortality. Regulatory T cell (Treg) therapy holds significant promise as a strategy to facilitate immunosuppression minimization. Polyclonal Treg therapy has been assessed...

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Detalles Bibliográficos
Autores principales: Alzhrani, Alaa, Bottomley, Matthew, Wood, Kathryn, Hester, Joanna, Issa, Fadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482792/
https://www.ncbi.nlm.nih.gov/pubmed/32977154
http://dx.doi.org/10.1016/j.cellimm.2020.104214