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A Novel Blood-Brain Barrier-Permeable Chemotherapeutic Agent for the Treatment of Glioblastoma

Introduction The standard treatment for glioblastoma (GBM) patients is surgical tumor resection, followed by radiation and chemotherapy with temozolomide (TMZ). Unfortunately, 60% of newly diagnosed GBM patients express high levels of the DNA repair enzyme O6-methylguanine-DNA methyltransferase (MGM...

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Detalles Bibliográficos
Autores principales:	Ozawa, Tomoko, Rodriguez, Mirna, Zhao, Guisheng, Yao, Tsun Wen, Fischer, Wolf-Nicolas, Jandeleit, Bernd, Koller, Kerry, Nicolaides, Theodore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cureus 2021
Materias:	Neurosurgery
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482806/ https://www.ncbi.nlm.nih.gov/pubmed/34646647 http://dx.doi.org/10.7759/cureus.17595

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