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Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy

AIMS: Pathological cardiac remodelling and subsequent heart failure represents an unmet clinical need. Long non-coding RNAs (lncRNAs) are emerging as crucial molecular orchestrators of disease processes, including that of heart diseases. Here, we report on the powerful therapeutic potential of the c...

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Detalles Bibliográficos
Autores principales: Viereck, Janika, Bührke, Anne, Foinquinos, Ariana, Chatterjee, Shambhabi, Kleeberger, Jan A, Xiao, Ke, Janssen-Peters, Heike, Batkai, Sandor, Ramanujam, Deepak, Kraft, Theresia, Cebotari, Serghei, Gueler, Faikah, Beyer, Andreas M, Schmitz, Jessica, Bräsen, Jan H, Schmitto, Jan D, Gyöngyösi, Mariann, Löser, Alexandra, Hirt, Marc N, Eschenhagen, Thomas, Engelhardt, Stefan, Bär, Christian, Thum, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482849/
https://www.ncbi.nlm.nih.gov/pubmed/32657324
http://dx.doi.org/10.1093/eurheartj/ehaa519

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