Cargando…

An evaluation of a FluoroSpot assay as a diagnostic tool to determine SARS-CoV-2 specific T cell responses

Numerous assays evaluating serological and cellular responses have been developed to characterize immune responses against SARS-CoV-2. Serological assays are both cost- and time-effective compared to cellular assays, but cellular immune responses may provide a diagnostic value to determine previous...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mangsbo, Sara M., Havervall, Sebastian, Laurén, Ida, Lindsay, Robin, Jernbom Falk, August, Marking, Ulrika, Lord, Martin, Buggert, Marcus, Dönnes, Pierre, Christoffersson, Gustaf, Nilsson, Peter, Hober, Sophia, Phillipson, Mia, Klingström, Jonas, Thålin, Charlotte
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483319/ https://www.ncbi.nlm.nih.gov/pubmed/34591918 http://dx.doi.org/10.1371/journal.pone.0258041

Ejemplares similares

Impact of SARS‐CoV‐2 infection on vaccine‐induced immune responses over time
por: Havervall, Sebastian, et al.
Publicado: (2022)

Duration of SARS-CoV-2 Immune Responses Up to Six Months Following Homologous or Heterologous Primary Immunization with ChAdOx1 nCoV-19 and BNT162b2 mRNA Vaccines
por: Marking, Ulrika, et al.
Publicado: (2022)

Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID‐19
por: Havervall, Sebastian, et al.
Publicado: (2021)

Immune responses after omicron infection in triple-vaccinated health-care workers with and without previous SARS-CoV-2 infection
por: Blom, Kim, et al.
Publicado: (2022)

Antibody responses after a single dose of ChAdOx1 nCoV-19 vaccine in healthcare workers previously infected with SARS-CoV-2
por: Havervall, Sebastian, et al.
Publicado: (2021)

Correlates of protection and viral load trajectories in omicron breakthrough infections in triple vaccinated healthcare workers
por: Marking, Ulrika, et al.
Publicado: (2023)

Long‐term SARS‐CoV‐2‐specific and cross‐reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology
por: Laurén, Ida, et al.
Publicado: (2022)

Stepping up ELISpot: Multi-Level Analysis in FluoroSpot Assays
por: Janetzki, Sylvia, et al.
Publicado: (2014)

Validation of an IFNγ/IL2 FluoroSpot assay for clinical trial monitoring
por: Körber, Nina, et al.
Publicado: (2016)

FluoroSpot assay to analyze SARS-CoV-2-specific T cell responses
por: Tiezzi, Camilla, et al.
Publicado: (2023)

SARS-CoV-2 induces a durable and antigen specific humoral immunity after asymptomatic to mild COVID-19 infection
por: Havervall, Sebastian, et al.
Publicado: (2022)

Anti-Spike Mucosal IgA Protection against SARS-CoV-2 Omicron Infection
por: Havervall, Sebastian, et al.
Publicado: (2022)

FluoroSpot Analysis of TLR-Activated Monocytes Reveals Several Distinct Cytokine-Secreting Subpopulations
por: Smedman, C, et al.
Publicado: (2012)

Point prevalence of SARS-CoV-2 infection among healthcare workers in March and June 2023 in Sweden
por: Blom, Kim, et al.
Publicado: (2023)

Mucosal immune responses following a fourth SARS-CoV-2 vaccine dose
por: Bladh, Oscar, et al.
Publicado: (2023)

Infection Rate of SARS-CoV-2 in Asymptomatic Healthcare Workers, Sweden, June 2022
por: Blom, Kim, et al.
Publicado: (2022)

The neutrophil: one cell on many missions or many cells with different agendas?
por: Christoffersson, Gustaf, et al.
Publicado: (2018)

Analysis of allelic cross-reactivity of monoclonal IgG antibodies by a multiplexed reverse FluoroSpot assay
por: Hoffmann-Veltung, Henriette, et al.
Publicado: (2022)

Combined Antigen-Specific Interferon-γ and Interleukin-2 Release Assay (FluoroSpot) for the Diagnosis of Mycobacterium tuberculosis Infection
por: Chesov, Dumitru, et al.
Publicado: (2015)

Four-Parameter FluoroSpot Assay Reveals That the Varicella Zoster Virus Elicits a Robust Memory T Cell IL-10 Response throughout Childhood
por: Nilsson, Anna, et al.
Publicado: (2022)

Triple Cytokine FluoroSpot Analysis of Human Antigen-Specific IFN-γ, IL-17A and IL-22 Responses
por: Dillenbeck, Tomas, et al.
Publicado: (2014)

Comparison of ELISpot and FluoroSpot in the Analysis of Swine Flu-Specific IgG and IgA Secretion by in Vivo Activated Human B Cells
por: Kesa, Gun, et al.
Publicado: (2012)

Increased Recruitment but Impaired Function of Leukocytes during Inflammation in Mouse Models of Type 1 and Type 2 Diabetes
por: Pettersson, Ulrika Sofia, et al.
Publicado: (2011)

SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden
por: Rudberg, Ann-Sofie, et al.
Publicado: (2020)

Utility of interferon gamma/tumor necrosis factor alpha FluoroSpot assay in differentiation between active tuberculosis and latent tuberculosis infection: a pilot study
por: Zhang, Lifan, et al.
Publicado: (2021)

7-month duration of SARS-CoV-2 mucosal immunoglobulin-A responses and protection
por: Marking, Ulrika, et al.
Publicado: (2023)

Memory B-Cell Responses Against Merozoite Antigens After Acute Plasmodium falciparum Malaria, Assessed Over One Year Using a Novel Multiplexed FluoroSpot Assay
por: Jahnmatz, Peter, et al.
Publicado: (2021)

A cell-free high throughput assay for assessment of SARS-CoV-2 neutralizing antibodies
por: Mravinacova, Sara, et al.
Publicado: (2022)

Turning Up the Heat: Local Temperature Control During in vivo Imaging of Immune Cells
por: Ahl, David, et al.
Publicado: (2019)

A FluoroSpot B assay for the detection of IgA and IgG SARS-CoV-2 spike-specific memory B cells: Optimization and qualification for use in COVID-19 vaccine trials
por: Bisceglia, Hélène, et al.
Publicado: (2023)

A modified method for rapid quantification of Chlamydia muridarum using Fluorospot
por: Keck, Jonathon, et al.
Publicado: (2019)

The anti‐inflammatory peptide Catestatin blocks chemotaxis
por: Muntjewerff, Elke M., et al.
Publicado: (2021)

Immune monitoring technology primer: the enzyme-linked immunospot (Elispot) and Fluorospot assay
por: Janetzki, Sylvia
Publicado: (2015)

Clinical and Experimental Pancreatic Islet Transplantation to Striated Muscle: Establishment of a Vascular System Similar to That in Native Islets
por: Christoffersson, Gustaf, et al.
Publicado: (2010)

IL-6 signalling biomarkers in hospitalised patients with moderate to severe SARS-CoV-2 infection in a single centre study in Sweden
por: Ziegler, Louise, et al.
Publicado: (2022)

A Deeper Look into Type 1 Diabetes – Imaging Immune Responses during Onset of Disease
por: Christoffersson, Gustaf, et al.
Publicado: (2016)

Simultaneous Detection of Antigen-Specific IgG- and IgM-Secreting Cells with a B Cell Fluorospot Assay
por: Bonsignori, Mattia, et al.
Publicado: (2012)

Bioengineering with Endothelial Progenitor Cells Improves the Vascular Engraftment of Transplanted Human Islets
por: Grapensparr, Liza, et al.
Publicado: (2018)

Three-dimensional Co-culture Model for Live Imaging of Pancreatic Islets, Immune Cells, and Neurons in Agarose Gel
por: Muntjewerff, Elke M., et al.
Publicado: (2023)

Impact of monocyte‐related modulators and kidney function on mortality in hospitalized patients with COVID‐19
por: Sendic, Senka, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_414svsk0q08142ct8qkfq8ggan