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Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis

STING is a nodal point for cellular innate immune response to microbial infections, autoimmunity and cancer; it triggers the synthesis of the antiviral proteins, type I interferons. Many DNA viruses, including Herpes Simplex Virus 1 (HSV1), trigger STING signaling causing inhibition of virus replica...

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Detalles Bibliográficos
Autores principales: Sharma, Nikhil, Wang, Chenyao, Kessler, Patricia, Sen, Ganes C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483329/
https://www.ncbi.nlm.nih.gov/pubmed/34591940
http://dx.doi.org/10.1371/journal.ppat.1009950