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Targeting anaplastic lymphoma kinase (ALK) gene alterations in neuroblastoma by using alkylating pyrrole-imidazole polyamides

Anaplastic lymphoma kinase (ALK) aberration is related to high-risk neuroblastomas and is an important therapeutic target. As acquired resistance to ALK tyrosine kinase inhibitors is inevitable, novel anti-ALK drug development is necessary in order to overcome potential drug resistance against ATP-c...

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Detalles Bibliográficos
Autores principales:	Ota, Yoko, Yoda, Hiroyuki, Inoue, Takahiro, Watanabe, Takayoshi, Shinozaki, Yoshinao, Takatori, Atsushi, Nagase, Hiroki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483358/ https://www.ncbi.nlm.nih.gov/pubmed/34591871 http://dx.doi.org/10.1371/journal.pone.0257718

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