Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge

A continuing challenge in modern medicine is the identification of safer and more efficacious drugs. Precision therapeutics, which have one molecular target, have been long promised to be safer and more effective than traditional therapies. This approach has proven to be challenging for multiple rea...

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Detalles Bibliográficos
Autores principales: Xiong, Zhaoping, Jeon, Minji, Allaway, Robert J., Kang, Jaewoo, Park, Donghyeon, Lee, Jinhyuk, Jeon, Hwisang, Ko, Miyoung, Jiang, Hualiang, Zheng, Mingyue, Tan, Aik Choon, Guo, Xindi, Dang, Kristen K., Tropsha, Alex, Hecht, Chana, Das, Tirtha K., Carlson, Heather A., Abagyan, Ruben, Guinney, Justin, Schlessinger, Avner, Cagan, Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483411/
https://www.ncbi.nlm.nih.gov/pubmed/34520464
http://dx.doi.org/10.1371/journal.pcbi.1009302

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