PCV2 targets cGAS to inhibit type I interferon induction to promote other DNA virus infection

Viruses use diverse strategies to impair the antiviral immunity of host in order to promote infection and pathogenesis. Herein, we found that PCV2 infection promotes the infection of DNA viruses through inhibiting IFN-β induction in vivo and in vitro. In the early phase of infection, PCV2 promotes t...

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Detalles Bibliográficos
Autores principales: Wang, Zhenyu, Chen, Jing, Wu, Xingchen, Ma, Dan, Zhang, Xiaohua, Li, Ruizhen, Han, Cong, Liu, Haixin, Yin, Xiangrui, Du, Qian, Tong, Dewen, Huang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483418/
https://www.ncbi.nlm.nih.gov/pubmed/34543359
http://dx.doi.org/10.1371/journal.ppat.1009940

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