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Dual-Wavelength Gated oxo-Diels–Alder Photoligation

[Image: see text] The control of chemical functionalization with orthogonal light stimuli paves the way toward manipulating materials with unprecedented spatiotemporal resolution. To reach this goal, we herein introduce a photochemical reaction system that enables two-color control of covalent ligat...

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Detalles Bibliográficos
Autores principales: Villabona, Marc, Wiedbrauk, Sandra, Feist, Florian, Guirado, Gonzalo, Hernando, Jordi, Barner-Kowollik, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483443/
https://www.ncbi.nlm.nih.gov/pubmed/33620229
http://dx.doi.org/10.1021/acs.orglett.1c00015
Descripción
Sumario:[Image: see text] The control of chemical functionalization with orthogonal light stimuli paves the way toward manipulating materials with unprecedented spatiotemporal resolution. To reach this goal, we herein introduce a photochemical reaction system that enables two-color control of covalent ligation via an oxo-Diels–Alder cycloaddition between two separate light-responsive molecular entities: a UV-activated photocaged diene based on ortho-quinodimethanes and a carbonyl dienophile appended to a diarylethene photoswitch, whose reactivity can be modulated upon illumination with UV and visible light.