Cargando…

Cardiovascular Development and Congenital Heart Disease Modeling in the Pig

BACKGROUND: Modeling cardiovascular diseases in mice has provided invaluable insights into the cause of congenital heart disease. However, the small size of the mouse heart has precluded translational studies. Given current high‐efficiency gene editing, congenital heart disease modeling in other spe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gabriel, George C., Devine, William, Redel, Bethany K., Whitworth, Kristin M., Samuel, Melissa, Spate, Lee D., Cecil, Raissa F., Prather, Randall S., Wu, Yijen, Wells, Kevin D., Lo, Cecilia W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483476/ https://www.ncbi.nlm.nih.gov/pubmed/34219463 http://dx.doi.org/10.1161/JAHA.121.021631

Ejemplares similares

Profiling development of abdominal organs in the pig
por: Gabriel, George C., et al.
Publicado: (2022)

Dickkopf-Related Protein 1 Inhibits the WNT Signaling Pathway and Improves Pig Oocyte Maturation
por: Spate, Lee D., et al.
Publicado: (2014)

Glycine supplementation in vitro enhances porcine preimplantation embryo cell number and decreases apoptosis but does not lead to live births
por: Redel, Bethany K., et al.
Publicado: (2016)

Improvement of in vitro and early in utero porcine clone development after somatic donor cells are cultured under hypoxia
por: Mordhorst, Bethany R., et al.
Publicado: (2019)

Improvements in pig agriculture through gene editing
por: Whitworth, Kristin M., et al.
Publicado: (2022)

Challenges and Considerations during In Vitro Production of Porcine Embryos
por: Chen, Paula R., et al.
Publicado: (2021)

Zygote injection of CRISPR/Cas9 RNA successfully modifies the target gene without delaying blastocyst development or altering the sex ratio in pigs
por: Whitworth, Kristin M., et al.
Publicado: (2016)

Chemical simulation of hypoxia in donor cells improves development of somatic cell nuclear transfer‐derived embryos and increases abundance of transcripts related to glycolysis
por: Cecil, Raissa F., et al.
Publicado: (2020)

Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection
por: Chen, Paula R., et al.
Publicado: (2022)

Inactivation of porcine interleukin-1β results in failure of rapid conceptus elongation
por: Whyte, Jeffrey J., et al.
Publicado: (2018)

Removal of hypotaurine from porcine embryo culture medium does not impair development of in vitro‐fertilized or somatic cell nuclear transfer‐derived embryos at low oxygen tension
por: Chen, Paula R., et al.
Publicado: (2020)

Resistance to coronavirus infection in amino peptidase N-deficient pigs
por: Whitworth, Kristin M., et al.
Publicado: (2018)

The use of cells from ANPEP knockout pigs to evaluate the role of aminopeptidase N (APN) as a receptor for porcine deltacoronavirus (PDCoV)
por: Stoian, Ana, et al.
Publicado: (2020)

High-Throughput Cryopreservation of In Vivo-Derived Swine Embryos
por: Spate, Lee D., et al.
Publicado: (2013)

Serologic titers to Leptospira in vaccinated pigs and interpretation for surveillance
por: Schommer, Susan K., et al.
Publicado: (2021)

Cryopreservation of In Vitro-Produced Early-Stage Porcine Embryos in a Closed System
por: Men, Hongsheng, et al.
Publicado: (2015)

Knockout of maternal CD163 protects fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV)
por: Prather, Randall S., et al.
Publicado: (2017)

Glutaminolysis is involved in the activation of mTORC1 in in vitro‐produced porcine embryos
por: Chen, Paula R., et al.
Publicado: (2021)

Improved cryopreservation of in vitro produced bovine embryos using FGF2, LIF, and IGF1
por: Stoecklein, Katy S., et al.
Publicado: (2021)

A porcine model of phenylketonuria generated by CRISPR/Cas9 genome editing
por: Koppes, Erik A., et al.
Publicado: (2020)

Creating genetically modified pigs by using nuclear transfer
por: Lai, Liangxue, et al.
Publicado: (2003)

Use of gene-editing technology to introduce targeted modifications in pigs
por: Ryu, Junghyun, et al.
Publicado: (2018)

Characterization of Green Fluorescent Protein in Heart Valves of a Transgenic Swine Model for Partial Heart Transplant Research
por: Bishara, Katherine, et al.
Publicado: (2023)

Congenital Heart Defects and Ciliopathies Associated With Renal Phenotypes
por: Gabriel, George C., et al.
Publicado: (2018)

Leukemia Inhibitory Factor (LIF)-dependent, Pluripotent Stem Cells Established from Inner Cell Mass of Porcine Embryos
por: Telugu, Bhanu Prakash V. L., et al.
Publicado: (2011)

Pharmacologic Reprogramming Designed to Induce a Warburg Effect in Porcine Fetal Fibroblasts Alters Gene Expression and Quantities of Metabolites from Conditioned Media Without Increased Cell Proliferation
por: Mordhorst, Bethany R., et al.
Publicado: (2018)

Genetics of Congenital Heart Disease
por: Williams, Kylia, et al.
Publicado: (2019)

Limited Expansion of Human Hepatocytes in FAH/RAG2-Deficient Swine
por: Nelson, Erek David, et al.
Publicado: (2022)

Genetic link between renal birth defects and congenital heart disease
por: San Agustin, Jovenal T., et al.
Publicado: (2016)

Engineering protein processing of the mammary gland to produce abundant hemophilia B therapy in milk
por: Zhao, Jianguo, et al.
Publicado: (2015)

Erratum: Genetic link between renal birth defects and congenital heart disease
por: San Agustin, Jovenal T., et al.
Publicado: (2016)

Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs
por: Kwon, Deug-Nam, et al.
Publicado: (2013)

EDUCATIONAL SERIES IN CONGENITAL HEART DISEASE: Cardiovascular MRI and CT in congenital heart disease
por: Pushparajah, Kuberan, et al.
Publicado: (2019)

Differential effect of anesthetics on mucociliary clearance in vivo in mice
por: Feldman, Kyle S., et al.
Publicado: (2021)

Insights into the genetic architecture of congenital heart disease from animal modeling
por: Zhu, Wenjuan, et al.
Publicado: (2023)

Disruption of Mitochondrion-To-Nucleus Interaction in Deceased Cloned Piglets
por: Park, Joonghoon, et al.
Publicado: (2015)

Swine models, genomic tools and services to enhance our understanding of human health and diseases
por: Walters, Eric M, et al.
Publicado: (2017)

Common deletion variants causing protocadherin-α deficiency contribute to the complex genetics of BAV and left-sided congenital heart disease
por: Teekakirikul, Polakit, et al.
Publicado: (2021)

Porcine Fetal-Derived Fibroblasts Alter Gene Expression and Mitochondria to Compensate for Hypoxic Stress During Culture
por: Mordhorst, Bethany R., et al.
Publicado: (2018)

The Treatment of Congenital Talipes Equino-Varus
por: Calvert, Cecil A.
Publicado: (1933)

Cannot write session to /tmp/vufind_sessions/sess_6vu0k4r9u0tvq51gfrv51pkkov