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Prohibitin‐1 Is a Dynamically Regulated Blood Protein With Cardioprotective Effects in Sepsis

BACKGROUND: In sepsis, circulating cytokines and lipopolysaccharide elicit mitochondrial dysfunction and cardiomyopathy, a major cause of morbidity and mortality with this condition. Emerging research places the PHB1 (lipid raft protein prohibitin‐1) at the nexus of inflammation, metabolism, and oxi...

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Detalles Bibliográficos
Autores principales: Mattox, Taylor A., Psaltis, Christine, Weihbrecht, Katie, Robidoux, Jacques, Kilburg‐Basnyat, Brita, Murphy, Michael P., Gowdy, Kymberly M., Anderson, Ethan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483490/
https://www.ncbi.nlm.nih.gov/pubmed/34219469
http://dx.doi.org/10.1161/JAHA.120.019877