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Implantable Cardioverter‐Defibrillator Shocks During COVID‐19 Outbreak

BACKGROUND: COVID‐19 was temporally associated with an increase in out‐of‐hospital cardiac arrests, but the underlying mechanisms are unclear. We sought to determine if patients with implantable defibrillators residing in areas with high COVID‐19 activity experienced an increase in defibrillator sho...

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Autores principales: Adabag, Selçuk, Zimmerman, Patrick, Black, Adam, Madjid, Mohammad, Safavi‐Naeini, Payam, Cheng, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483533/
https://www.ncbi.nlm.nih.gov/pubmed/34044586
http://dx.doi.org/10.1161/JAHA.120.019708
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author Adabag, Selçuk
Zimmerman, Patrick
Black, Adam
Madjid, Mohammad
Safavi‐Naeini, Payam
Cheng, Alan
author_facet Adabag, Selçuk
Zimmerman, Patrick
Black, Adam
Madjid, Mohammad
Safavi‐Naeini, Payam
Cheng, Alan
author_sort Adabag, Selçuk
collection PubMed
description BACKGROUND: COVID‐19 was temporally associated with an increase in out‐of‐hospital cardiac arrests, but the underlying mechanisms are unclear. We sought to determine if patients with implantable defibrillators residing in areas with high COVID‐19 activity experienced an increase in defibrillator shocks during the COVID‐19 outbreak. METHODS AND RESULTS: Using the Medtronic (Mounds View, MN) Carelink database from 2019 and 2020, we retrospectively determined the incidence of implantable defibrillator shock episodes among patients residing in New York City, New Orleans, LA, and Boston, MA. A total of 14 665 patients with a Medtronic implantable defibrillator (age, 66±13 years; and 72% men) were included in the analysis. Comparing analysis time periods coinciding with the COVID‐19 outbreak in 2020 with the same periods in 2019, we observed a larger mean rate of defibrillator shock episodes per 1000 patients in New York City (17.8 versus 11.7, respectively), New Orleans (26.4 versus 13.5, respectively), and Boston (30.9 versus 20.6, respectively) during the COVID‐19 surge. Age‐ and sex‐adjusted hurdle model showed that the Poisson distribution rate of defibrillator shocks for patients with ≥1 shock was 3.11 times larger (95% CI, 1.08–8.99; P=0.036) in New York City, 3.74 times larger (95% CI, 0.88–15.89; P=0.074) in New Orleans, and 1.97 times larger (95% CI, 0.69–5.61; P=0.202) in Boston in 2020 versus 2019. However, the binomial odds of any given patient having a shock episode was not different in 2020 versus 2019. CONCLUSIONS: Defibrillator shock episodes increased during the higher COVID‐19 activity in New York City, New Orleans, and Boston. These observations may provide insights into COVID‐19–related increase in cardiac arrests.
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spelling pubmed-84835332021-10-06 Implantable Cardioverter‐Defibrillator Shocks During COVID‐19 Outbreak Adabag, Selçuk Zimmerman, Patrick Black, Adam Madjid, Mohammad Safavi‐Naeini, Payam Cheng, Alan J Am Heart Assoc Brief Communication BACKGROUND: COVID‐19 was temporally associated with an increase in out‐of‐hospital cardiac arrests, but the underlying mechanisms are unclear. We sought to determine if patients with implantable defibrillators residing in areas with high COVID‐19 activity experienced an increase in defibrillator shocks during the COVID‐19 outbreak. METHODS AND RESULTS: Using the Medtronic (Mounds View, MN) Carelink database from 2019 and 2020, we retrospectively determined the incidence of implantable defibrillator shock episodes among patients residing in New York City, New Orleans, LA, and Boston, MA. A total of 14 665 patients with a Medtronic implantable defibrillator (age, 66±13 years; and 72% men) were included in the analysis. Comparing analysis time periods coinciding with the COVID‐19 outbreak in 2020 with the same periods in 2019, we observed a larger mean rate of defibrillator shock episodes per 1000 patients in New York City (17.8 versus 11.7, respectively), New Orleans (26.4 versus 13.5, respectively), and Boston (30.9 versus 20.6, respectively) during the COVID‐19 surge. Age‐ and sex‐adjusted hurdle model showed that the Poisson distribution rate of defibrillator shocks for patients with ≥1 shock was 3.11 times larger (95% CI, 1.08–8.99; P=0.036) in New York City, 3.74 times larger (95% CI, 0.88–15.89; P=0.074) in New Orleans, and 1.97 times larger (95% CI, 0.69–5.61; P=0.202) in Boston in 2020 versus 2019. However, the binomial odds of any given patient having a shock episode was not different in 2020 versus 2019. CONCLUSIONS: Defibrillator shock episodes increased during the higher COVID‐19 activity in New York City, New Orleans, and Boston. These observations may provide insights into COVID‐19–related increase in cardiac arrests. John Wiley and Sons Inc. 2021-05-28 /pmc/articles/PMC8483533/ /pubmed/34044586 http://dx.doi.org/10.1161/JAHA.120.019708 Text en © 2021 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Brief Communication
Adabag, Selçuk
Zimmerman, Patrick
Black, Adam
Madjid, Mohammad
Safavi‐Naeini, Payam
Cheng, Alan
Implantable Cardioverter‐Defibrillator Shocks During COVID‐19 Outbreak
title Implantable Cardioverter‐Defibrillator Shocks During COVID‐19 Outbreak
title_full Implantable Cardioverter‐Defibrillator Shocks During COVID‐19 Outbreak
title_fullStr Implantable Cardioverter‐Defibrillator Shocks During COVID‐19 Outbreak
title_full_unstemmed Implantable Cardioverter‐Defibrillator Shocks During COVID‐19 Outbreak
title_short Implantable Cardioverter‐Defibrillator Shocks During COVID‐19 Outbreak
title_sort implantable cardioverter‐defibrillator shocks during covid‐19 outbreak
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483533/
https://www.ncbi.nlm.nih.gov/pubmed/34044586
http://dx.doi.org/10.1161/JAHA.120.019708
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