PRMT5 regulates ovarian follicle development by facilitating Wt1 translation

Protein arginine methyltransferase 5 (Prmt5) is the major type II enzyme responsible for symmetric dimethylation of arginine. Here, we found that PRMT5 was expressed at high level in ovarian granulosa cells of growing follicles. Inactivation of Prmt5 in granulosa cells resulted in aberrant follicle...

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Detalles Bibliográficos
Autores principales: Chen, Min, Dong, Fangfang, Shen, Zhiming, Wu, Haowei, Cen, Changhuo, Cui, Xiuhong, Bao, Shilai, Gao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483736/
https://www.ncbi.nlm.nih.gov/pubmed/34448450
http://dx.doi.org/10.7554/eLife.68930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483736/
https://www.ncbi.nlm.nih.gov/pubmed/34448450
http://dx.doi.org/10.7554/eLife.68930

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