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Comparison of small symptomatic and asymptomatic abdominal aortic aneurysms based on computational fluid dynamics analysis

BACKGROUND: The purpose of this study was to compare the hemodynamic parameters of symptomatic and asymptomatic abdominal aortic aneurysms (AAAs) to explore the risk factors for AAA rupture. METHODS: We conducted a retrospective analysis of 26 patients with symptomatic small AAAs and 60 patients wit...

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Autores principales: Zhou, Zhijun, Teng, Biyun, Zhao, Yu, Wang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483881/
https://www.ncbi.nlm.nih.gov/pubmed/34596128
http://dx.doi.org/10.1097/MD.0000000000027306
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author Zhou, Zhijun
Teng, Biyun
Zhao, Yu
Wang, Zhe
author_facet Zhou, Zhijun
Teng, Biyun
Zhao, Yu
Wang, Zhe
author_sort Zhou, Zhijun
collection PubMed
description BACKGROUND: The purpose of this study was to compare the hemodynamic parameters of symptomatic and asymptomatic abdominal aortic aneurysms (AAAs) to explore the risk factors for AAA rupture. METHODS: We conducted a retrospective analysis of 26 patients with symptomatic small AAAs and 60 patients with asymptomatic small AAAs. Computational fluid dynamics methods were used to compare hemodynamic characteristics between the symptomatic and asymptomatic groups and to evaluate risk factors for the occurrence of symptomatic AAAs. RESULTS: The maximum diameters in the symptomatic and asymptomatic groups were 49.7 ± 4.94 mm and 48.4 ± 4.55 mm, respectively. Wall shear stress values at turbulent flow regions in the symptomatic and asymptomatic groups were 0.0098 ± 0.0084 Pa versus 0.0174 ± 0.0068 Pa, respectively. Shear stress values at the site with maximal blood flow impact force in the symptomatic and asymptomatic groups were 1.13 ± 0.466 Pa and 2.04 ± 0.42 Pa, respectively. The areas of the intra-luminal thrombus in the section with the maximum diameter in the symptomatic and asymptomatic groups were 952.19 ± 413.53 mm(2) versus 646.63 ± 296.88 mm(2), respectively. CONCLUSION: The wall shear stress in the symptomatic group was lower than that in the asymptomatic group.
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spelling pubmed-84838812021-10-04 Comparison of small symptomatic and asymptomatic abdominal aortic aneurysms based on computational fluid dynamics analysis Zhou, Zhijun Teng, Biyun Zhao, Yu Wang, Zhe Medicine (Baltimore) 3400 BACKGROUND: The purpose of this study was to compare the hemodynamic parameters of symptomatic and asymptomatic abdominal aortic aneurysms (AAAs) to explore the risk factors for AAA rupture. METHODS: We conducted a retrospective analysis of 26 patients with symptomatic small AAAs and 60 patients with asymptomatic small AAAs. Computational fluid dynamics methods were used to compare hemodynamic characteristics between the symptomatic and asymptomatic groups and to evaluate risk factors for the occurrence of symptomatic AAAs. RESULTS: The maximum diameters in the symptomatic and asymptomatic groups were 49.7 ± 4.94 mm and 48.4 ± 4.55 mm, respectively. Wall shear stress values at turbulent flow regions in the symptomatic and asymptomatic groups were 0.0098 ± 0.0084 Pa versus 0.0174 ± 0.0068 Pa, respectively. Shear stress values at the site with maximal blood flow impact force in the symptomatic and asymptomatic groups were 1.13 ± 0.466 Pa and 2.04 ± 0.42 Pa, respectively. The areas of the intra-luminal thrombus in the section with the maximum diameter in the symptomatic and asymptomatic groups were 952.19 ± 413.53 mm(2) versus 646.63 ± 296.88 mm(2), respectively. CONCLUSION: The wall shear stress in the symptomatic group was lower than that in the asymptomatic group. Lippincott Williams & Wilkins 2021-10-01 /pmc/articles/PMC8483881/ /pubmed/34596128 http://dx.doi.org/10.1097/MD.0000000000027306 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle 3400
Zhou, Zhijun
Teng, Biyun
Zhao, Yu
Wang, Zhe
Comparison of small symptomatic and asymptomatic abdominal aortic aneurysms based on computational fluid dynamics analysis
title Comparison of small symptomatic and asymptomatic abdominal aortic aneurysms based on computational fluid dynamics analysis
title_full Comparison of small symptomatic and asymptomatic abdominal aortic aneurysms based on computational fluid dynamics analysis
title_fullStr Comparison of small symptomatic and asymptomatic abdominal aortic aneurysms based on computational fluid dynamics analysis
title_full_unstemmed Comparison of small symptomatic and asymptomatic abdominal aortic aneurysms based on computational fluid dynamics analysis
title_short Comparison of small symptomatic and asymptomatic abdominal aortic aneurysms based on computational fluid dynamics analysis
title_sort comparison of small symptomatic and asymptomatic abdominal aortic aneurysms based on computational fluid dynamics analysis
topic 3400
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483881/
https://www.ncbi.nlm.nih.gov/pubmed/34596128
http://dx.doi.org/10.1097/MD.0000000000027306
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