NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization

5-Methylcytosine (m(5)C) is a posttranscriptional RNA modification participating in many critical bioprocesses, but its functions in human cancer remain unclear. Here, by detecting the transcriptome-wide m(5)C profiling in esophageal squamous cell carcinoma (ESCC), we showed increased m(5)C methylat...

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Detalles Bibliográficos
Autores principales: Su, Jiachun, Wu, Guandi, Ye, Ying, Zhang, Jialiang, Zeng, Lingxing, Huang, Xudong, Zheng, Yanfen, Bai, Ruihong, Zhuang, Lisha, Li, Mei, Pan, Ling, Deng, Junge, Li, Rui, Deng, Shuang, Zhang, Shaoping, Zuo, Zhixiang, Liu, Zexian, Lin, Junzhong, Lin, Dongxin, Zheng, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484015/
https://www.ncbi.nlm.nih.gov/pubmed/34345012
http://dx.doi.org/10.1038/s41388-021-01978-0

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