Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

Behaviors and disorders related to self-regulation, such as substance use, antisocial behavior, and ADHD, are collectively referred to as externalizing and have shared genetic liability. We applied a multivariate approach that leverages genetic correlations among externalizing traits for genome-wide...

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Detalles Bibliográficos
Autores principales: Linnér, Richard Karlsson, Mallard, Travis T., Barr, Peter B., Sanchez-Roige, Sandra, Madole, James W., Driver, Morgan N., Poore, Holly E., de Vlaming, Ronald, Grotzinger, Andrew D., Tielbeek, Jorim J., Johnson, Emma C., Liu, Mengzhen, Rosenthal, Sara Brin, Ideker, Trey, Zhou, Hang, Kember, Rachel L., Pasman, Joëlle A., Verweij, Karin J.H., Liu, Dajiang J., Vrieze, Scott, Kranzler, Henry R., Gelernter, Joel, Harris, Kathleen Mullan, Tucker-Drob, Elliot M., Waldman, Irwin D., Palmer, Abraham A., Harden, K. Paige, Koellinger, Philipp D., Dick, Danielle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484054/
https://www.ncbi.nlm.nih.gov/pubmed/34446935
http://dx.doi.org/10.1038/s41593-021-00908-3

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