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Knockdown of the prognostic cancer stem cell marker Musashi-1 decreases radio-resistance while enhancing apoptosis in hormone receptor-positive breast cancer cells via p21(WAF1/CIP1)

PURPOSE: While the stem cell marker Musashi-1 (MSI-1) has been identified as a key player in a wide array of malignancies, few findings exist on its prognostic relevance and relevance for cancer cell death and therapy resistance in breast cancer. METHODS: First, we determined prognostic relevance of...

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Detalles Bibliográficos
Autores principales: Troschel, Fabian M., Palenta, Heike, Borrmann, Katrin, Heshe, Kristin, Hua, San Hue, Yip, George W., Kiesel, Ludwig, Eich, Hans Theodor, Götte, Martin, Greve, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484224/
https://www.ncbi.nlm.nih.gov/pubmed/34291358
http://dx.doi.org/10.1007/s00432-021-03743-y