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A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis

In addition to increasing the expression of programmed death-ligand 1 (PD-L1), tumor cells can also secrete exosomal PD-L1 to suppress T cell activity. Emerging evidence has revealed that exosomal PD-L1 resists immune checkpoint blockade, and may contribute to resistance to therapy. In this scenario...

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Detalles Bibliográficos
Autores principales: Wang, Guohao, Xie, Lisi, Li, Bei, Sang, Wei, Yan, Jie, Li, Jie, Tian, Hao, Li, Wenxi, Zhang, Zhan, Tian, Ye, Dai, Yunlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484261/
https://www.ncbi.nlm.nih.gov/pubmed/34593794
http://dx.doi.org/10.1038/s41467-021-25990-w