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A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis
In addition to increasing the expression of programmed death-ligand 1 (PD-L1), tumor cells can also secrete exosomal PD-L1 to suppress T cell activity. Emerging evidence has revealed that exosomal PD-L1 resists immune checkpoint blockade, and may contribute to resistance to therapy. In this scenario...
Autores principales: | Wang, Guohao, Xie, Lisi, Li, Bei, Sang, Wei, Yan, Jie, Li, Jie, Tian, Hao, Li, Wenxi, Zhang, Zhan, Tian, Ye, Dai, Yunlu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484261/ https://www.ncbi.nlm.nih.gov/pubmed/34593794 http://dx.doi.org/10.1038/s41467-021-25990-w |
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